|Background||Noroviruses are a kind of single-stranded, positivesense RNA viruses belonging to the family Caliciviridae (Sapoviruses also belong to this family, among others). They are highly contagious viruses whose main routes of transmission are: person-to-person contact and through contaminated food/water (in the U.S. is estimated that they account for 50% of gastrointestinal outbreaks by food poisoning). They often cause large outbreaks in closed communities in a variety of environments such as hospitals, nursing homes, schools, kindergarten, restaurants, cruises where, once the virus has been introduced, the infection spreads very quickly. Several studies show that Noroviruses are responsible for almost 50% of gastroenteritis outbreaks worldwide (considering all outbreaks of any aetiology). Human Noroviruses have been very difficult to study because of their high diversity and the lack of an efficient cell culture for "in vitro" replication as well as a suitable animal model. The cloning of genomes of Norovirus and expression of the viral capsid proteins in baculovirus and other expression systems, have allowed to obtain "virus-like particles" (VLP) which, once assembled, are able to recreate the real structure of the virus. Norovirus capsid is composed of a single major structural protein, the capsid protein (VP1) which can be divided into two main domains: the shell (S) and the protruding domains (P). .|
|Description||The Rapid E.coli O157:H7 is a one step coloured chromatographic immunoassay for the qualitative detection of Escherichia coli O157 in stool samples.|
|Components||1. Card tests 2. Sample diluent 3. Instructions for use 4. Stool collection tubes|
|Storage||Store at 15-25°C, DO NOT FREEZE or use beyond the expiration date. The shelf life is 35 months.|
For Research Use Only.