|Background||Clostridium difficile is an anaerobic, Gram-positive, spore- forming bacteria that is carried by approximately 5% of the healthy population. Following hospitalisation, the carrier rate climbs to approximately 30%, leading to the development of nosocomial infection. Children are colonised by C.difficile early after birth, but they do not appear to suffer any clinical symptoms despite intensive investigations. The current discussion suggests a lack of enteric receptors for the toxins or differences in faecal pH in children that prevent toxin activity. C.difficile can produce different toxins: Toxin A (TcdA) (308 kDa) is called an enterotoxin given that it can induce full symptoms in the hamster animal model. TcdA also displays high cytotoxicity but only on specific TcdA sensitive cells such as HT-295. Toxin B (TcdB) (279 kDa) is classified as a cytotoxin. In the majority of cells cultured in laboratories (e.g. Vero, CHO or HELA) it is about 1,000 times more potent than toxin A. The TcdB amino acid sequence varies between different strains.|
|Description||Rapid Norovirus test is a chromatographic immunoassay for the qualitative detection, in separate bands, of Genogroup I (GI) and Genogroup II (GII) of Norovirus in human faeces. A positive signal in either test bands provides a good indication that we may be in presence of a Norovirus infection which|
|Components||1. Reaction devices (Card or Blister formats) 2. Sample dilution buffer 3. Non-graduated disposable plastic pipettes (yellow) 4. Graduated disposable plastic pipettes (only Blister format) 5. Wooden applicators for solid samples. 6. 1.5 ml plastic micro-t|
|Storage||Store at 15-25°C, DO NOT FREEZE or use beyond the expiration date. The shelf life is 34 months.|
For Research Use Only.